Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10223646
rs10223646
DSE
0.010 GeneticVariation BEFREE The SNPs in tight linkage disequilibrium with the TSPYL1 rs10223646 SNP were significantly correlated with baseline severity of depression in patients with MDD in the Sequenced Treatment Alternatives to Relieve Depression and International SSRI Pharmacogenomics Consortium clinical trials. 31628858

2020

dbSNP: rs1333045
rs1333045
0.010 GeneticVariation BEFREE The rs1333045 was associated with MDD in recessive model (OR (95% CI) = 2.221 (1.173-4.207), adjusted p value = 0.026). 31773399

2020

dbSNP: rs1333048
rs1333048
0.010 GeneticVariation BEFREE Haplotype analyses have shown that T A haplotype block (rs1333045 and rs1333048 respectively) significantly decreases risk of addiction, BP I, BP II, and MDD. 31773399

2020

dbSNP: rs1512325
rs1512325
0.010 GeneticVariation BEFREE The rs1512325 in NR3C2 gene and TSH concentration may be related to venlafaxine treatment outcome in Chinese Han MDD patients. 31757642

2020

dbSNP: rs2535629
rs2535629
A 0.820 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019

dbSNP: rs10774037
rs10774037
A 0.800 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019

dbSNP: rs4765914
rs4765914
T 0.800 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019

dbSNP: rs12415800
rs12415800
0.720 GeneticVariation BEFREE A recent genome-wide association study (GWAS) for major depressive disorder (MDD) in Chinese women identified a single-nucleotide polymorphism (SNP), rs12415800, near the Sirtuin1 (SIRT1) gene as one of the top candidate loci. 31176830

2019

dbSNP: rs12415800
rs12415800
0.720 GeneticVariation BEFREE Besides, in independent Han Chinese postmortem brain and peripheral blood samples, the MDD risk allele of rs12415800 predicted lower SIRT1 mRNA levels, which was consistent with the reduced expression of this gene in MDD patients compared with healthy subjects. 31819045

2019

dbSNP: rs7597593
rs7597593
T 0.710 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913

2019

dbSNP: rs1002656
rs1002656
C 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs10061069
rs10061069
G 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs10149470
rs10149470
A 0.700 GeneticVariation GWASCAT Identification of common genetic risk variants for autism spectrum disorder. 30804558

2019

dbSNP: rs10149470
rs10149470
G 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs1021363
rs1021363
A 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs10243383
rs10243383
T 0.700 GeneticVariation GWASCAT GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort. 30219690

2019

dbSNP: rs1045430
rs1045430
G 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs10789214
rs10789214
T 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs10789340
rs10789340
0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474

2019

dbSNP: rs10817969
rs10817969
T 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs10890020
rs10890020
G 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs10913112
rs10913112
C 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs1095626
rs1095626
C 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

dbSNP: rs11004733
rs11004733
C 0.700 GeneticVariation GWASCAT GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. 31164008

2019

dbSNP: rs111326206
rs111326206
C 0.700 GeneticVariation GWASCAT GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. 31164008

2019